Red de Trastornos Adictivos - BARCELONA 2014 Summer Course "Cellular Biology of Addiction" (partnered with the CSHL)
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BARCELONA 2014 Summer Course "Cellular Biology of Addiction" (partnered with the CSHL) PDF Imprimir E-Mail

- Name(s) of the organizer(s): Rafael Maldonado (University Pompeu Fabra, Barcelona, Spain), Brigitte L. Kieffer (IGBMC/University of Strasburg, Illkirch, France), Chris Evans (University of California, Los Angeles, USA), Mark von Zastrow (University of California, San Francisco, USA) and Antonello Bonci (National Institute on Drug Abuse-NIDA, Baltimore, USA)

 

- Name and address of the contact person: Miquel-Angel Serra, Laboratory of Neuropharmacology, University Pompeu Fabra, Barcelona Biomedical Research Park (PRBB), c/ Dr Aiguader, 88, 08003 Barcelona, Spain

 

- Telephone of the contact person: +34 93 3160866

 

- E-mail address of the contact person: Esta dirección de correo electrónico está protegida contra los robots de spam, necesita tener Javascript activado para poder verla

 

- Title of the event: Summer Course "Cellular Biology of Addiction"

 

- Link for students (pre)registration: http://eventum.upf.edu/go/cellularbiologyaddiction

- Short description, topic and purpose:

 

This event is organised by the University Pompeu Fabra (UPF, Spain) and the Cold Spring Harbor Laboratory (CSHL, USA), and is supported by the National Institute on Drug Abuse (NIDA). The conference will follow the current CSHL course format (see the 2013 edition at http://meetings.cshl.edu/courses/c-drug13.shtml).

 

The primary objective of the workshop is to provide an intense discussion of the fundamentals, state-of-the-art advances and major gaps in the cell and molecular biology of drug addiction. Targeted to both new and experienced investigators, the workshop will combine formal presentations and informal discussions to convey the merits and excitement of cellular and molecular approaches to drug addiction research. The workshop will stress the significance of this approach not only to the most costly neuropsychiatric disorder, addiction, but its applicability to learning, memory, neurochemical correlates of reward, perception and other disciplines of neuroscience. Research on the molecular and cellular changes that occur in response to drugs is critical for clarifying whether adaptive processes are diverse for each stage of addiction and for each drug of abuse. With the advent of genomics and proteomics, an extraordinary opportunity now exists to develop comprehensive models of neuroadaptative processes fundamental to addiction, craving, and relapse to drug use. The workshop will provide attendees with a spectrum of disciplines that can contribute to developing comprehensive models of each stage of drug addiction. The following disciplines will be presented: 1.Overview of addiction. 2. Neuroadaptation to drugs of abuse. 3. Association between drug-induced neuroadaptation and behavioral manifestations 4. Genotype/susceptibility to drug addiction or drug response. 5. Tolerance, sensitization and adaptation at the cellular level. 6. New receptor targets. 7. Drug discovery and development to treat drug abuse: how can cell biology contribute? This workshop will provide an integrated view of current and novel research on neuroadaptive responses to addiction, foster discussion on collaboration and integration and provide critical information needed to construct a model of addiction as a disease and novel molecular targets for biological treatments. Beyond the plane of scientific endeavour, such information is vital for formulating public policy and for enlightening the public on the neurobiological consequences of drug use and addiction. The proposed workshop will generate intense interest, open conduits for collaborations and novel routes to investigating the neurobiology of addiction. The workshop makes particular efforts to include a diverse group of participants, being particularly mindful of the inclusion of women and a good balance of European and North American scientists.

 

-  Dates: 13-20 July, 2014

 

- Venue: Barcelona Biomedical Research Park (PRBB), c/ Dr Aiguader, 88, 08003 Barcelona, Spain

 

- Proposed programme

 

a. Trainee Candidates

 

The course will accept a maximum of twenty-four (24) students ranging from graduate students (typically, PhD students) to senior investigators. Applications are open to individuals at any stage of their careers. Applications are open to individuals at universities and colleges, medical research institutions and industry.  Women and minority applicants are encouraged. Moreover, the PRBB facilities are prepared for persons with reduced mobility. Scholarships to students coming from less-developed countries are planned.

 

b. Workshop outline

 

The overall theme of the course for the 2014 edition is the new therapeutic strategies for addiction. Thus, this second edition will cover translational and clinical aspects of drug addiction, although both basic and clinical aspects will be taken in consideration. Therefore, the list of speakers encompasses both basic investigators and clinicians.

 

c. Schedule

 

The course will typically have 4 speakers each day (for an overall number of 24 lecturers for the whole course, from Monday to Saturday), 2 in the morning (9,30-13 h) and 2 in the afternoon (14,30-18 h); each session will begin with a 1 h lecture by the invited speakers followed by 30 min discussion, with a break between speakers. Guest lecturers will generally stay at the PRBB for at least one day to respond to questions and issues that may arise. Each evening session is dedicated to the attendees who present their research informally. This venue will elicit strong support from all and lead to much discussion and potential collaborations. We will videotape the course and distribute the video recordings via the internet. A social program will be organized.

 

3. Faculty members

 

Rafael Maldonado (UPF), Brigitte L. Kieffer (CERBM/Universiy of Strasburg), Chris Evans (UCLA), Mark Von Zastrow (UCSF) and Antonello Bonci (NIDA) will be the course directors. In addition, at least one US instructor will be going to Barcelona. 

 

4. List of speakers

 

On the basis of 4 speakers per day, for 6 days (Monday-Saturday), a maximum of 24 lecturers (including the Instructors) are planned covering a wide range of topics within the major theme of the course, the new therapeutic strategies of substances of abuse. An opening and a closing lecture are planned.

 

-          Jon-Kar Zubieta (University of Michigan, Ann Arbor, WI, USA; neurobiological mechanisms underlying the regulation of stress responses towards the understanding of mood disorders and affective regulation, as well as substance abuse disorders and pain).

-          Angus C. Nairn (Yale University, New Haven, USA; Cell and molecular mechanisms of addiction.

-          Marina R. Picciotto (Yale University, New Haven, USA; Mechanism of nicotine addiction.

-          Markus Heilig (NIAA, Rockville, MD, USA; alcohol addiction, basic and clinic).

-          Scott Sternson (Howard Hughes Medical Institute, Janelia Farm Research Campus, Ashburn, VA, USA; Circuit mechanisms underlying basic motivations).

-          Charles Chavkin (University of Washington, Seattle, WA, USA; Kappa systems in addiction).

-          Anatol Kreitzer (Gladstone Institute of Neurological Disease, University of California, San Francisco, CA, USA; optogenetics approaches to addiction).

-          George F Koob (Scripps Research Institute, La Jolla, CA, USA; From Jan. 2014, NIAA, Rockville, MD, USA). Pending

-          David Belin (University of Poitiers, Poitiers, France; Addiction and habit learning).

-          Pier Vincenzo Piazza (Magendie Neurocentre, Bordeaux, France; Modeling DSMIV criteria in rodents).

-          Rainer Spanagel (Central Institute of Mental Health, University of Heidelberg, Mannheim, Germany, alcohol-translational).

-          Andreas Zimmer (University of Bonn, Bonn, Germany; endocannabinoid and/or endogenous opioids in addiction).

-          Thorgeir Thorgeirsson (DeCode Genetics, Reykjavik, Iceland; human genetics and addiction).

-          Kelly Tan (University of Genève, Geneve, Switzerland; drug reinforcement and addiction, GABAergic transmission and the reward circuit).

-          Cyril Herry (INSERM U862, Neurocenter Magendie, Bordeaux, France; drug addiction and fear behavior).

-          Jeff Dalley (Department of Psychology, University of Cambridge, Cambridge, UK; addiction, compulsitivity and impulsivity).

-          Chris J. Evans (University of California, Los Angeles, CA, USA; opioids and opiod addiction).

-          Brigitte L. Kieffer (CERBM and University of Strasburg, Illkirch, France, Genetic approaches to study opioid addiction).

-          Rafael Maldonado (University Pompeu Fabra, Barcelona, Spain; behavioral models for the study of the neurobiological substrate of drug addiciton).

-          Jonathan D. Pollock (National Institute on Drug Abuse, Bethesda, USA; funding opportunities in addiction research).

 

 
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